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He also frequently appeared alongside River Song (Alex Kingston), a fellow time traveller with whom he shared a romantic storyline, and was the last Doctor to appear alongside the long-serving companion Sarah Jane Smith (Elisabeth Sladen) prior to the actress' death, featuring in two episodes of the spin-off programme The Sarah Jane Adventures.
The Doctor is a very special part, and it takes a very special actor to play him.
After appearing in Victorian period clothing throughout "The Snowmen", the Doctor rejects his tweed jacket ("The Bells of Saint John") in favour of a purple-brown cashmere frock coat and a variety of waistcoats, and generally more sober colours of shirt and bow tie.
Amy Pond's reading glasses, which were left behind with the Doctor after Amy and Rory's departure in the episode "The Angels Take Manhattan", are also occasionally worn.
Within the show's narrative, the Doctor is a centuries-old Time Lord from the planet Gallifrey, who travels in time and space in his TARDIS, frequently with companions.
At the end of life, the Doctor can regenerate his body; in doing so, his personality and physical appearance change.
The Doctor also confronts his dark side in "Amy's Choice", where he is put through trials by a manifestation of his self-loathing, the Dream Lord (Toby Jones).
Smith debuts fully in "The Eleventh Hour", where he first meets Amy Pond (Karen Gillan) as a child while investigating a mysterious crack in her wall.
Many years later, Amy joins the Doctor as his travelling companion on the eve of her marriage to Rory Williams (Arthur Darvill).
Steven Moffat describes the Eleventh Doctor as an "old man trapped in a young man's body" and Matt Smith characterises him as someone with "a lot of blood on his hands" who copes via constant travelling and thrill-seeking.
Karen Gillan as Amy Pond, with Matt Smith as the Eleventh Doctor, filming "The Eleventh Hour"; Smith is wearing a tattered version of his predecessor's costume, which led to the Eleventh Doctor earning the nickname "Raggedy Doctor." (2009) The Eleventh Doctor first appears in the final scene of The End of Time (2010) when his previous incarnation regenerates.
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In this episode the Doctor wears his most famous "Prince of Wales check" tweed jacket which he wears, with some switching to a green military coat, until parting ways with Amy and Rory in "The Angels Take Manhattan".